Research Article
Dickson Onyenmulo Uwaya*
Dickson Onyenmulo Uwaya*
Corresponding Author
Department of
Science Laboratory Technology, Faculty of Life Sciences, University of Benin,
Benin City, Nigeria.
E-mail: dickson.uwaya@uniben.edu; udickson4christ@yahoo.com,
Tel: (+234) 705-965-0758
Saratu Nuhu Musa
Saratu Nuhu Musa
Department of
Science Laboratory Technology, Faculty of Life Sciences, University of Benin,
Benin City, Nigeria.
E-mail: sarafinanuhu@gmail.com, Tel: +234) 8038161950
John C. Atughara
John C. Atughara
4 Middlewood Street, Salford, M54LH, United Kingdom
E-mail: obinna.kenan@gmail.com
Abstract
Polyherbal
remedies is a crucial aspect of traditional medicine with combine multiple
herbs in a single formulation, enhancing the efficacy and reducing toxicity.
This study evaluate the aphrodisiac potential of the polyherbal-formulated tea
(Zingiber
officinale, Allium sativum, Azanza garckeana, Ageratum conyzoides, and Anthocleista
djalonensis). Twenty male rats were divided into
five groups of four rats each. Group 1 received distilled water; groups 2 and 3
received 10 and 20 mg/kg of tea extract, group 4 received 5 mg/kg of
sildenafil; and group 5 received 20 mg/kg of carbamazepine orally for 14 days.
The rats were assessed for mating, orientational behaviour, and testosterone
analysis. The study found that polyherbal
tea extract at 20 mg/kg and sildenafil (5 mg/kg) significantly increased the
mounting and intromission frequency compared to normal control and
carbamazepine (p < 0.01). Aqueous
extract of tea (10 and 20 mg/kg) and 5 mg/kg of sildenafil increase ejaculatory
frequency and latency when compared to normal control and carbamazepine (p < 0.05). Polyherbal tea (10 and 20
mg/kg), 20 mg/kg of carbamazepine, and 5 mg/kg of sildenafil significantly
increased the number of anogenital sniffing, licking, and genital grooming when
compared to water control (p < 0.05).
Aqueous extract of the tea (10 and 20 mg/kg) and 5 mg/kg of sildenafil increase
testosterone levels when compared to water control and carbamazepine (p < 0.05). The weight of the testis
remained unaltered. In conclusion, polyherbal-formulated tea possesses
aphrodisiac properties and enhance sexual health and performance in male rats.
Keywords
Aphrodisiac, carbamazepine, Polyherbal-formulated, sildenafil, Testosterone
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This work is licensed under the
Creative Commons Attribution
4.0
License (CC BY-NC 4.0).
Abstract
Polyherbal
remedies is a crucial aspect of traditional medicine with combine multiple
herbs in a single formulation, enhancing the efficacy and reducing toxicity.
This study evaluate the aphrodisiac potential of the polyherbal-formulated tea
(Zingiber
officinale, Allium sativum, Azanza garckeana, Ageratum conyzoides, and Anthocleista
djalonensis). Twenty male rats were divided into
five groups of four rats each. Group 1 received distilled water; groups 2 and 3
received 10 and 20 mg/kg of tea extract, group 4 received 5 mg/kg of
sildenafil; and group 5 received 20 mg/kg of carbamazepine orally for 14 days.
The rats were assessed for mating, orientational behaviour, and testosterone
analysis. The study found that polyherbal
tea extract at 20 mg/kg and sildenafil (5 mg/kg) significantly increased the
mounting and intromission frequency compared to normal control and
carbamazepine (p < 0.01). Aqueous
extract of tea (10 and 20 mg/kg) and 5 mg/kg of sildenafil increase ejaculatory
frequency and latency when compared to normal control and carbamazepine (p < 0.05). Polyherbal tea (10 and 20
mg/kg), 20 mg/kg of carbamazepine, and 5 mg/kg of sildenafil significantly
increased the number of anogenital sniffing, licking, and genital grooming when
compared to water control (p < 0.05).
Aqueous extract of the tea (10 and 20 mg/kg) and 5 mg/kg of sildenafil increase
testosterone levels when compared to water control and carbamazepine (p < 0.05). The weight of the testis
remained unaltered. In conclusion, polyherbal-formulated tea possesses
aphrodisiac properties and enhance sexual health and performance in male rats.
Abstract Keywords
Aphrodisiac, carbamazepine, Polyherbal-formulated, sildenafil, Testosterone

This work is licensed under the
Creative Commons Attribution
4.0
License (CC BY-NC 4.0).

Editor-in-Chief

This work is licensed under the
Creative Commons Attribution 4.0
License.(CC BY-NC 4.0).